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Meta-analysis of validation data sets assessing the association between the MANBA, CXCR5, SOX8, RPS6KB1 and ZBTB46 loci and multiple sclerosis risk in populations of European descent. The x-axis depicts the odds ratio (OR). Study-specific odds ratios (black squares) and 95% confidence intervals (CIs, lines) were calculated using an additive model. The summary odds ratios and 95% confidence intervals (grey diamonds) were calculated based on fixed-effect meta-analysis.
