Table 3.

Observed-to-Expected Ratio, by Patient and Tumor Characteristics

Characteristics	Breast		Colorectal		Lung		Melanoma		Prostate		Pancreas
	O/E ratio	Z- scorea	O/E ratio	Z- score	O/E ratio	Z- score	O/E ratio	Z- score	O/E ratio	Z- score	O/E ratio	Z- score
Overall	0.97	3.95	0.98	5.09	0.90	70.1	1.07	5.12	1.02	4.29	0.92	39.1
Age (years)
18-49	0.96	4.12	0.92	6.11	0.89	24.3	0.97	1.04	0.95	1.09	0.91	14.1
50-74	0.97	3.44	0.96	8.08	0.90	65.5	1.19	8.59	1.00	0.71	0.91	37.9
75-90	1.02	2.10	1.03	4.83	0.93	20.2	1.00	0.26	1.07	6.56	0.94	12.0
Sex
Male	0.86	2.33	0.97	4.42	0.91	56.3	1.07	4.12	1.02	4.29	0.92	28.3
Female	0.97	3.76	0.98	2.76	0.90	42.6	1.08	3.11	-	-	0.92	27.0
Race
White	0.99	0.99	0.99	1.52	0.91	59.9	1.07	4.56	1.04	6.06	0.93	31.5
Black	0.92	5.78	0.95	4.45	0.90	28.7	0.80	1.88	0.99	0.10	0.89	18.4
Other	0.92	3.87	0.89	8.06	0.88	24.2	2.83	9.47	0.89	3.75	0.87	15.9
AJCC 6th Tumor Stage
I	-	-	1.33	10.9	-	-	2.12	25.7	-	-	0.95	2.85
IA	-	-	-	-	0.79	17.8	-	-	-	-	-	-
IB	-	-	-	-	0.87	15.7	-	-	-	-	-	-
II	-	-	-	-	-	-	0.95	2.20	-	-	0.95	9.54
IIA	1.09	7.58	1.04	3.59	0.88	6.35	-	-	-	-	-	-
IIB	0.96	3.31	0.96	1.81	0.88	16.7	-	-	-	-	-	-
III							0.96	1.53	-	-	0.94	10.8
IIIA	0.96	2.39	1.21	5.05	0.91	20.4	-	-	-	-	-	-
IIIB	0.93	6.33	1.00	0.86	0.92	41.7	-	-	-	-	-	-
IIIC	-	-	0.97	3.44	-	-	-	-	-	-	-	-
IV	0.92	16.2	0.93	29.0	0.91	79.3	0.83	15.2	1.02	4.29	0.90	46.3
Number of primaries
First and only	0.97	3.95	0.98	5.09	0.90	70.1	1.07	5.12	1.02	4.29	0.92	39.1
With multiple primaries (exclude first and only)	0.83	16.5	0.84	23.2	0.81	49.1	0.83	6.83	0.67	17.9	0.86	21.8

Abbreviations: AJCC, American Joint Committee on Cancer

^aZ-score> 1.96, p-value< 0.05; Z-score> 2.58, p-value< 0.01; Z-score> 3.29, p-value< 0.001