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. Author manuscript; available in PMC: 2013 Jun 5.
Published in final edited form as: Biochemistry. 2011 Oct 3;50(42):9088–9113. doi: 10.1021/bi201077h

Figure 21.

Figure 21

(a) CD titration of neomycin into i-motif DNA(50 uM/base pair). The spectrum with solid circle represents the one of DNA only. The inset shows CD spectra of DNA alone (continuous line) and ligand-saturated complex (dashed line). (b) UV melting profiles of i-motif DNA in the absence (1) and presence (2) neomycin at rbd 4. The experiments were conducted in buffer 10 mM sodium cacodylate, 0.5 mM EDTA, 100 mM NaCl at pH 6.8.