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Thermodynamic profile of neomycin-nucleic acid binding separated according to Gibb’s free energy equation components (Figure 19) and ranked accordingly: (a) ΔG (b) TΔS and (c) ΔH. The experiments were conducted in buffer 10 mM sodium cacodylate, 0.5 mM EDTA, 100 mM NaCl at pH 5.5.
