. Author manuscript; available in PMC: 2013 Jun 5.

Published in final edited form as: Biochemistry. 2012 Mar 9;51(11):2331–2347. doi: 10.1021/bi201657k

Table 2.

UV thermal denaturation data of HIV TAR RNA in the presence of increasing conc. of neomycin dimer (DPA52). Buffer conditions: 100 mM KCl, 10 mM SC, 0.5 mM EDTA, pH 6.8. [HIV TAR RNA] = 1 μM/strand. The heating rate was 0.3 °C.

Ratio (DPA52/TAR RNA)	T_m (°C)	ΔT_m (°C)
TAR RNA	68.9	-
1	78.2	9.3
2	80.4	11.5
4	81.3	12.4