. Author manuscript; available in PMC: 2013 Jun 5.

Published in final edited form as: Biochemistry. 2012 Mar 9;51(11):2331–2347. doi: 10.1021/bi201657k

Table 4.

Representative table of ethidium bromide displacement assay. Buffer conditions: 100 mM KCl, 10 mM SC, 0.5 mM EDTA, pH 6.8. HIV TAR RNA = 50 nM/strand.

Ligand	Linker length	IC₅₀ (nM)
DPA51	7	56
DPA52	7	52
DPA65	7	36
DPA53	8	67
DPA54	8	81
DPA55	10	99
DPA56	10	97
DPA58	16	67
DPA60	20	74
Neomycin	NA	417