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The inhibition effect of neomycin dimers on HIV antigen synthesis in treated cells.
| Compound | Concentration (μM) |
% of HIV antigen synthesis | ||
|---|---|---|---|---|
|
| ||||
| Day 2 | Day 4 | Day 6 | ||
|
| ||||
| DPA52 | 25 | 15% | 100% | 100% |
| DPA53 | 9 | 2% | 40% | 100% |
| DPA54 | 17 | 3-5% | 80% | 100% |
| DPA55 | 4 | 3-5% | 30% | 100% |
| DPA56 | 8 | 5-7% | 40% | 100% |
| Virus Control | NA | 15% | 100% | 100% |
