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. Author manuscript; available in PMC: 2013 Jun 5.
Published in final edited form as: Trends Parasitol. 2012 Jan 23;28(3):90–92. doi: 10.1016/j.pt.2011.12.003

Figure 1. Transgenic parasites facilitate monitoring of mice infections.

Figure 1

Mice infected with Trypanosoma cruzi expressing luciferase (6) (a), Plasmodium berghei expressing luciferase (10) during liver stage (b) and blood stage (c) infections. The luminescent signal is quantified by the imager (IVIS lumina), and it is proportional to parasite load during infection. (d)

The effect of benznidazole (BZ) treatment (100 mg/kg i.p. on days 2 and 3 post-infection) on the expansion of tandem tomato (TdT) fluorescent protein-expressing T. cruzi in the footpads of mice is shown.