FIGURE 7. Phagocytosis of complement-bound ICs by monocyte/macrophages is inhibited in P. yoelii infected mice.
Splenocytes from P. yoelii-infected or uninfected control mice were cultured for 30 min in vitro in the presence of FITC-labeled OVA-ICs pre-incubated or not with mouse control serum (complement bound ICs). A) Phagocytosis of IC by CD11b+F4/80+ cells from control mice (gray line) or infected mice (black line). B) Average mean fluorescence intensity (MFI) of FITC-labeled IC in CD11b+F4/80+ cells from control and infected mice (n=3). *** p < 0.001 when compared to control.