Table 2.
gutwrencher Mutants Have Fewer Enteric Neurons Than Wild-Type Siblings
| |
|
Mean cell counts |
Fold change (p value) |
||||
|---|---|---|---|---|---|---|---|
| Intestinal region | Genotype | All neurons | 5HT neurons | EE cells | All neurons | 5HT neurons | EE cells |
| Mid-intestine | Wild-type | 98.6 | 6.4 | 8.8 | 9.5 (1.2e−6) | 6.4 (0.006) | 1.0 (0.959) |
| gutwrencher | 10.4 | 1.0 | 8.6 | ||||
| Vent | Wild-type | 66.8 | 1.8 | 9.4 | 56 (5.8e−7) | undef. (0.001) | 1.3 (0.665) |
| gutwrencher | 1.2 | 0.0 | 7.4 | ||||
Cell counts were performed on 200 μm lengths of dissected intestine. 5HT-positive, Elavl-negative cells were counted as enteroendocrine cells (EE cells). P values were calculated via two-tailed unpaired Student's t-test. Undef. represents the undefined value of any value divided by zero.