Table 2.
Domain | Symptom | Activity | Impact | Total |
FEV1% | ||||
Baseline | −0.33 (.002) | −0.35 (.0007) | −0.26 (.01) | −0.33 (.001) |
6 mo | −0.41 (.0001) | −0.48 (< .0001) | −0.42 (< .0001) | −0.49 (< .0001) |
12 mo | −0.35 (.002) | −0.46 (< .0001) | −0.29 (.01) | −0.40 (.0005) |
Dlco% | ||||
Baseline | −0.21 (.048) | −0.43 (< .0001) | −0.20 (.06) | −0.33 (.002) |
6 mo | −0.30 (.006) | −0.49 (< .0001) | −0.34 (.002) | −0.45 (< .0001) |
12 mo | −0.17 (.14) | −0.54 (< .0001) | −0.33 (.005) | −0.41 (.0004) |
6MWD | ||||
Baseline | −0.14 (.19) | −0.36 (.0005) | −0.13 (.23) | −0.23 (.03) |
6 mo | −0.28 (.01) | −0.45 (< .0001) | −0.37 (.0006) | −0.46 (< .0001) |
12 mo | −0.20 (.08) | −0.49 (< .0001) | −0.37 (.001) | −0.41 (.0003) |
Log(VEGF-D) | ||||
Baseline | 0.09 (.42) | 0.23 (.03) | 0.18 (.10) | 0.23 (.03) |
6 mo | 0.21 (.07) | 0.27 (.02) | 0.10 (.37) | 0.19 (.09) |
12 mo | 0.19 (.12) | 0.23 (.06) | 0.15 (.20) | 0.21 (.08) |
Values are Spearman correlation coefficients (P value). See Table 1 legend for expansion of abbreviations.