Table 3.
Baseline cardiovascular disease group separately by gender: prevalent electrocardiographic myocardial infarction/ischemia for prediction of coronary heart disease death and total mortality by Novacode and Minnesota Code criteria
| Total (n = 1,113) |
Event (rate)* |
HR† (95% CI) |
p Value‡ | ||
|---|---|---|---|---|---|
| Women | Men | Women | Men | ||
| Coronary heart disease death (n = 124/561 for women, n = 164/552 for men) |
|||||
| Myocardial infarction by Novacode§ | 35 (27%) | 61 (34%) | 1.79 (1.12–2.84) | 1.72 (1.22–2.44) | 0.6984 |
| Myocardial infarction by Minnesota Code§ | 38 (22%) | 64 (30%) | 1.11 (0.71–1.74) | 1.19 (0.84–1.68) | 0.8201 |
| Major Q/ST-T change by Novacode§ | 73 (30%) | 91 (35%) | 2.19 (1.44–3.33) | 2.11 (1.50–2.97) | 0.5321 |
| Major Q/ST-T change by Minnesota Code§ | 71 (26%) | 96 (33%) | 1.52 (1.00–2.31) | 1.68 (1.19–2.37) | 0.6563 |
| Total mortality (n = 414/561 for women, n = 460/552 for men) | |||||
| Myocardial infarction by Novacode | 107 (81%) | 160 (88%) | 1.47 (1.14–1.90) | 1.46 (1.19–1.80) | 0.9280 |
| Myocardial infarction by Minnesota Code | 133 (76%) | 184 (86%) | 1.31 (1.04–1.65) | 1.30 (1.05–1.60) | 0.6246 |
| Major Q/ST-T change by Novacode | 199 (82%) | 229 (88%) | 1.47 (1.17–1.84) | 1.47 (1.20–1.79) | 0.8741 |
| Major Q/ST-T change by Minnesota Code | 218 (79%) | 251 (87%) | 1.40 (1.12–1.75) | 1.39 (1.13–1.70) | 0.5221 |
Event rate is number of events divided by number in that category (percentage) of electrocardiographic myocardial infarction/ischemia by Minnesota Code/Novacode.
Adjusted for key demographic and clinical variables of age, race, education, smoking status, alcohol use, diabetes, hypertension, cancer, increased angina, body mass index, systolic blood pressure, hematocrit, white blood cell count, ankle– brachial index, baseline glucose, insulin, and creatinine.
Assessing equivalence of hazard ratios for men and women.
CI = confidence interval; HR = hazard ratio.