Table 2.

Weight, growth, adiposity, food intake, and hormones in 15-wk-old male rats after electrolytic lesion at age of 8 wk

	VMN sham	VMN	VMN/DMN	CHML sham	CMHL
Body weight (g)	363 ± 6.2	423 ± 24*	451 ± 16†	392.0 ± 13.93	465.4 ± 22.5*
Length (mm)	236.2 ± 2.1	233.0 ± 3.4	236.8 ± 2.7	238.8 ± 2.9	225.4 ± 1.8†
Lee index	0.301 ± 0.002	0.320 ± 0.003‡	0.322 ± 0.005†	0.303 ± 0.003	0.342 ± 0.006‡
Food intake§	19.3 ± 0.6	24.0 ± 1.1†	28.0 ± 1.9†	19.4 ± 0.4	31.9 ± 2.4†
Food intake∥	19.6 ± 0.9	21.3 ± 1.2	24.7 ± 1.8*	17.7 ± 0.9	26.3 ± 2.9*
Food intake¶	19.8 ± 1.4	21.0 ± 1.5	22.3 ± 0.9	18.6 ± 0.8	22.1 ± 1.6
Corticosterone (ng/mL)	360 ± 40	263 ± 38	261 ± 47	369 ± 45	344 ± 47
Testosterone (ng/mL)	383 ± 57	239 ± 111	193 ± 28*	187 ± 37	210 ± 74
Insulin (ng/mL)§	0.89 ± 0.22	1.22 ± 0.14	1.96 ± 0.31*	0.62 ± 0.18	1.52 ± 0.46*
Leptin (ng/mL)§	3.6 ± 0.6	8.6 ± 3.5	9.6 ± 2.6*	7.3 ± 1.0	46.8 ± 8.9†
IGF-1 (ng/mL)	736 ± 86	n.d.	374 ± 51†	921 ± 17	596 ± 8†

Summarized data from two experiments (experiment 1: sham, VMN, VMN/DMN; experiment 2: sham, CMHL). Values are represented as mean ± SEM.

^*p < 0.05.

^†p < 0.01.

^‡p < 0.001.

^§Age of 9 wk, 1 wk after lesion.

^∥Age of 12 wk, 4 wk after lesion.

^¶Age of 15 wk, 7 wk after lesion.

n.d., not determined.