Table 3.
Discrimination of the various multivariate models in the identification of COPD in subgroups of asymptomatic and symptomatic subjects
| |
Model |
C-index (95% CI) |
|
|---|---|---|---|
| Asymptomatics | Symptomatics | ||
| 1 |
Baseline model * |
0.674 (0.625 -0.722) |
0.634 (0.589 - 0.679) |
| 2 |
+ CT-BWT |
0.739 (0.695 - 0.783) |
0.764 (0.725 - 0.803) |
| 3 |
+ CT air trapping |
0.737 (0.693 - 0.780) |
0.794 (0.759 - 0.829) |
| 4 |
+ CT emphysema |
0.753 (0.707 – 0.800) |
0.806 (0.771 - 0.841) |
| 5 |
+ CT-BWT |
0.771 (0.730 – 0.813) |
0.821 (0.788 – 0.855) |
| + CT air trapping | |||
| 6 |
+ CT emphysema |
0.782 (0.740 - 0.824) |
0.872 (0.844 - 0.899) |
| + CT air trapping | |||
| 7 |
+ CT emphysema |
0.828 (0.790 – 0.866) |
0.886 (0.859 - 0.912) |
| + CT-BWT | |||
| 8 |
+ CT emphysema |
0.832 (0.795 – 0.869) |
0.905 (0.881 - 0.929) |
| |
+ CT-BWT |
|
|
| + CT air trapping | |||
* Model including age, body mass index, smoking status and packyears of smoking history; 95% CI = 95th percentile confidence interval; CT-BWT = Quantitatively assessed bronchial wall thickness.