Table 2.
Medical characteristics and treatments (compliance and side effects)
| n | % | ||
|---|---|---|---|
|
Medical characteristics |
Cadaveric donor transplantation |
1035 |
97.5% |
| Duration of transplantation, years |
8.5 ± 5.8 |
||
| Patients with rejection since renal transplant |
222 |
22.9% |
|
|
Major causes of ESRD | |||
| Chronic glomerular nephritis |
380 |
35.8% |
|
| Interstitial nephropathy |
122 |
11.5% |
|
| Hereditary nephropathy |
206 |
19.4% |
|
| Duration of dialysis, months (mean ± SD) |
31.3 ± 37.2 |
||
|
Intercurrent health events in the last four weeks |
245 |
23.2% |
|
| Hospitalization |
111 |
11.1% |
|
| Critical illness |
47 |
4.7% |
|
| Infectious disease |
123 |
13.7% |
|
| Acute rejection episodes |
42 |
4.0% |
|
| Graft surgery |
17 |
1.9% |
|
|
Comorbidities | |||
| Hypertension |
844 |
80.9% |
|
| BMI > 30 (kg/m2) |
140 |
13.4% |
|
| Diabetes mellitus |
133 |
12.9% |
|
| Current smokers |
122 |
11.8% |
|
|
Treatments, compliance and side |
Side effects |
838 |
79% |
| Mean number of side effects per patient |
5.7 ±3.9 |
||
| Range |
(1–17) |
||
| Mean number of drugs per patient |
5.1 ±3.1 |
||
|
Immunosuppressive treatment | |||
| Calcineurin inhibitors |
956 |
90.6% |
|
| Corticosteroids |
593 |
56.2% |
|
| Antimetabolites |
769 |
72.9% |
|
| Proliferation inhibitors |
53 |
5.0% |
|
| Monotherapy |
109 |
10.3% |
|
| Bitherapy |
564 |
53.5% |
|
| Tritherapy |
378 |
35.8% |
|
|
Other treatment | |||
| Antihypertensive drugs |
890 |
84.4% |
|
| Hypolipidemics |
540 |
51.2% |
|
| Antidiabetic agents |
100 |
9.5% |
|
| Non-compliant to treatment |
239 |
22.5% |
|
|
Side effects related to: | |||
| General health |
548 |
51.6% |
|
| Mental health |
467 |
44.0% |
|
| Body modification |
771 |
72.7% |
|
| Sexual disorders |
288 |
27.1% |
|
| Diarrhea | 216 | 20.4% | |