Table 3.
Clinical effectiveness of treatment group and control group (PP/ITT dataset)
| Variables | PP dataset | ITT dataset | ||||||
|---|---|---|---|---|---|---|---|---|
|
|
|
|||||||
| Ganciclovir in situ ophthalmic gel group | Ganciclovir ophthalmic gel group | P-value | Ganciclovir in situ ophthalmic gel group | Ganciclovir ophthalmic gel group | P-value | |||
| Clinical effectiveness | χ2 = 0.6331 | 0.4262 | χ2 = 0.49 | 0.4836 | ||||
| Total (%) | 102 (100.00) | 100 (100.00) | 108 (100.00) | 111 (100.00) | ||||
| Significantly effective (%) | 47 (46.08) | 43 (43.00) | 47 (43.52) | 45 (40.54) | ||||
| Effective (%) | 50 (49.02) | 50 (50.00) | 51 (47.22) | 53 (47.75) | ||||
| Slightly effective (%) | 4 (3.92) | 6 (6.00) | 5 (4.63) | 6 (5.41) | ||||
| Ineffective (%) | 1 (0.98) | 1 (1.00) | 5 (4.63) | 7 (6.31) | ||||
| Total clinical effectiveness | χ2 = 0.3978 | 0.5282 | χ2 = 0.3503 | 0.5540 | ||||
| CER (%) | 97 (95.10) | 93 (93.00) | 98 (90.74) | 98 (88.29) | ||||
| CIER (%) | 5 (4.90) | 7 (7.00) | 10 (9.26) | 13 (11.71) | ||||
| Confidence interval of 95% CER (%) | (90.91, 99.29) | (88.00, 98.00) | Z = 3.427 | 0.000305 | (85.27, 96.21) | (82.31, 94.27) | Z = 2.836 | 0.0022872 |
Abbreviations: PP, per-protocol; ITT, intent-to-treat; CER, clinical effective rate; CIER, clinical ineffective rate.