Table 4.
Positional candidate genes (PCG) within 1-Mb SNP window (SNPW) and their putative functions
| Chromosome | SNPW | PCG | Gene ontology |
|---|---|---|---|
| 2 |
19.11 - 19.97 |
AGPS |
It encodes a protein that catalyzes the step of lipid biosynthesis |
| |
|
|
and the removal of long chain acid anion |
| |
|
NFE2L2 |
It encodes a transcription factor which is a member of a small |
| |
|
|
family of basic Leucine (bZIP) proteins |
| 2 |
22.09 - 22.77 |
WIPF1 |
It encodes a protein that plays an important role in the organization |
| |
|
|
of the actin cytoskeleton |
| |
|
OLA1 |
It hydrolyzes ATP and can hydrolyze GTP with lower efficiency |
| |
|
SP3 |
regulates transcription by binding consensus GC and GT- box |
| |
|
|
elements in target genes |
| 12 |
53.01 - 53.99 |
SCEL |
It encodes a tissue-specific basic helix-loop-helix (bHLH) protein |
| |
|
|
with a pivotal role in hemopoises |
| |
|
EDNRB |
it mediates actin by association with G-Protein that activates |
| |
|
|
a phosphaidylinositol-calcium second messenger system |
| 13 |
14.36 - 14.92 |
VAMP7 |
It encodes a transmembrane protein that is a member of soluble |
| |
|
|
N-ethylmeleimide-sensitive factor attachment protein receptor |
| |
|
|
(SNARE) family |
| 21 |
19.00 - 19.98 |
NTRK3 |
It encodes a member of a neurotrophic tyrosine receptor kinase family |
| |
|
MIR1179 |
It involved in post transcriptional regulation of gene expression |
| MIR7-1 | It involved in post transcriptional regulation of gene expression |