Table 8.
Characteristics of 5847 successful SNPs based on data from an Illumina Infinium SNP array*
SNP characteristic | Mean | Median | Range |
---|---|---|---|
GenTrain score |
0.81 |
0.84 |
0.35-0.98 |
GC50 score (median GenCall score) |
0.78 |
0.87 |
0.15-0.99 |
Call frequency† |
0.99 |
1.00 |
0.85-1.00 |
Minor allele frequency (MAF) |
0.24 |
0.24 |
0.002-0.5 |
Heterozygosity (observed) |
0.33 |
0.36 |
0.00-1.00 |
Heterozygosity (expected) |
0.32 |
0.36 |
0.004-0.5 |
Number of SNPs with a significant HWE deviation = 263 (4.5%)§ |
*Successful SNPs are those with a call frequency > 0.85 and MAF > 0 based on an analysis of 260 trees.
† Successful calls are those with a GenCall score ≥ 0.15 [19].
§ Tested using an exact test of HWE and a probability level of 0.9 × 10-5 (i.e., Bonferroni-corrected P-value of 0.05 based on 5847 SNPs).