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. 2013 Jun 5;8(6):e65741. doi: 10.1371/journal.pone.0065741

Table 2. Altered transcripts with a link to apoptosis.

Anti-apoptotic Pro-apoptotic
Pathway Transcript HGERT/HG HG/NG Pathway Transcript HGERT/HG HG/NG
AKT/Bad pik3r1 1.03 Caspase hip1 1.05
AKT/FRAP1 ddit4l 0.97 Cell cycle maged1 1.01
BLK elf2 0.99 1.01 Cell cycle/CDK ccni 1.01
Caspase hspe1 0.99 Cell proliferation pdcd7 1.02 0.99
Caspase ifi6 1.13 Cell proliferation ubn1 1.02
Cell proliferation furin 1.02 DNA repair rrm2b 0.98
DNA repair actr5 1.01 FOX foxn3 1.01 0.99
FOX foxc1 1.01 FOX foxp1 1.01
Impedes cyt c release gsn 1.03 HER-2/NEU casc4 0.99 1.01
JNK/SAPK mbip 0.98 JNK/SAPK map4k3 0.98
p38 MAP kinase stk39 0.98 JNK/SAPK sos1 1.06 0.94
P53/XIAP inhibition notch1 1.02 MYC family mxd4 1.02 0.98
RAS rsu1 0.99 P53/CDK ccnk 1.01
RAS rhob 1.02 0.97 P53 rybp 1.01 0.99
RAS rhoj 1.02 P53 tp53bp2 1.01
RAS rab3b 1.07 P53 tbrg1 1.02 0.98
TGFβ acvr2a 0.99 P53 tp53i11 1.02 0.98
TGFβ bmp6 1.01 RAS rassf2 1.01 1.03
eng 1.01 0.98 WNT hbp1 0.99
atxn3 0.99 dap 1.01
pdcd6 0.99 serinc3 1.01 0.99
socs3 1.01 sox4 1.01 0.99
txndc5 1.03 lyn 1.02 0.99