Table 3. QPCR analysis of five genes (3p21.3) in cervical SCC.
| Genes | Frequency of mRNA level decrease, % |
Median of mRNA level decrease*, n-fold |
||||
|---|---|---|---|---|---|---|
| |
Without metastasis |
With metastasis |
Total |
Without metastasis |
With metastasis |
Total |
|
RASSF1A |
44 (4/9) |
70 (7/10) |
58 (11/19) |
3 (2 – 4) |
11 (2 – 74) |
4 (2 – 74) |
|
RBSP3 |
44 (4/9) |
90 (9/10) |
68 (13/19) |
3 (2 – 4) |
3 (2 – 11) |
3 (2 – 11) |
|
ITGA9 |
78 (7/9) |
100 (10/10) |
89 (17/19) |
6 (2 – 9) |
5 (3 – 78) |
6 (2 – 78) |
|
VILL |
44 (4/9) |
60 (6/10) |
53 (10/19) |
3 (2 – 4) |
4 (2 – 9) |
3 (2 – 9) |
| APRG1 | 57 (4/7) | 62 (5/8) | 60 (9/15) | 4 (2 – 18) | 5 (4 – 12) | 5 (2 – 18) |
*
A range of mRNA levels decrease is shown in parentheses. p < 0.01 for each gene.