Table 6.
Summary of Abnormal Neuroimaging Findings in 35 Children with Early Medical Intractability
| Finding | N with enduring intractability | N who achieved seizure freedom at final follow-up without surgery |
|---|---|---|
|
| ||
| Remote ischemia or atrophy | ||
| -generalized/multifocal | 6 | 2 |
| -hemispheric | 1 | 0 |
| -focal, extratemporal | 2 | 0 |
|
| ||
| Malformations of cortical development | ||
| -focal, extratemporal | 1 | 0 |
| -hemispheric | 2 | 0 |
| -generalized | 4 | 0 |
| -multifocal | 1* | 0 |
|
| ||
| Mesial temporal sclerosis alone | 3 | 0 |
|
| ||
| Mesial temporal sclerosis with periventricular leukomalacia | 1 | 0 |
|
| ||
| Tuberous sclerosis | 3 | 0 |
|
| ||
| Low grade tumor | 2 | 0 |
|
| ||
| Vascular malformation | ||
| -hemispheric – Sturge Weber | 1 | 0 |
| -focal, temporal | 1 | 0 |
| -focal, extratemporal | 1 | 0 |
|
| ||
| Hypothalamic hamartoma | 1 | 0 |
|
| ||
| Isolated agenesis of corpus callosum | 0 | 1 |
|
| ||
| Calcified granuloma | 1 | 0 |
|
| ||
| Focal inflammatory lesion in basal ganglia, not further defined | 1 | 0 |
*
also had associated mesial temporal sclerosis