Table 2.

pQCT and anthropometric Z-scores at enrollment and 12 months in ALL participants

	Z-score
	Baseline ALL vs. reference		12-Month ALL vs. reference		Changes within ALL (0–12 months)
	Mean ± sd	P value	Mean ± sd	P value	Mean (range)	P value
Anthropometry
Height	0.43 ± 0.93	0.17	0.42 ± 0.87	0.22	0.05 (−0.76–1.28)	0.34
BMI	0.97 ± 0.83	<0.001	0.89 ± 0.83	<0.001	−0.04 (−1.13–0.56)	0.44
BMD
Trabecular BMD	−1.03 ± 1.34	<0.001	−0.58 ± 1.41	<0.001	0.41 (−1.03–2.30)	<0.001
Cortical BMD	−0.84 ± 1.05	<0.001	−0.51 ± 0.91	<0.001	0.26 (−2.66–1.80)	0.06
Cortical dimensions
Cortical area	0.16 ± 1.18	0.23	0.63 ± 1.22	<0.001	0.48 (−0.63–1.19)	<0.001
Periosteal circ	0.11 ± 0.92	0.36	0.45 ± 1.02	<0.001	0.34 (−0.23–1.05)	<0.001
Endosteal circ	−0.07 ± 0.95	0.64	−0.11 ± 1.00	0.43	−0.06 (−3.30–2.95)	0.35
Body composition
Muscle area	0.24 ± 0.93	0.09	0.54 ± 0.92	<0.001	0.27 (−0.62–1.70)	<0.001
Fat area	0.67 ± 1.00	<0.001	0.51 ± 1.13	<0.001	−0.16 (−1.24–0.55)	<0.01