Table 3.

pQCT cortical Z-scores and changes in Z-scores from enrollment to 12 months in participants by interval since completion of ALL therapy

	Z-score		P value
	Early, n = 20	Late, n = 29
Cortical BMD
Baseline	−0.29 ± 0.93 (−2.22–1.24)	−1.17 ± 0.96 (−2.93–1.00)	<0.01
Follow-up	−0.73 ± 0.87 (−2.51–0.70)	−0.36 ± 0.97 (−1.95–1.67)	0.18
Change	−0.54 ± 0.85 (−2.66–0.86)	0.77 ± 0.46 (−0.07–1.80)	<0.001
Cortical area
Baseline	0.12 ± 0.81 (−0.94–1.86)	0.26 ± 1.34 (−4.09–2.23)	0.65
Follow-up	1.01 ± 0.96 (−0.90–2.39)	0.54 ± 1.24 (−2.86–2.90)	0.16
Change	0.82 ± 0.60 (−0.15–1.90)	0.28 ± 0.51 (−0.63–1.26)	<0.01
Periosteal circumference
Baseline	0.04 ± 0.70 (−0.99–1.47)	0.20 ± 1.04 (−1.46–2.01)	0.56
Follow-up	0.53 ± 0.92 (−1.01–2.21)	0.49 ± 1.06 (−1.27–2.62)	0.91
Change	0.46 ± 0.39 (−0.14–1.05)	0.27 ± 0.32 (−0.23–0.87)	0.09
Endosteal circumference
Baseline	−0.20 ± 0.89 (−2.46–1.25)	−0.01 ± 0.99 (−1.48–2.10)	0.51
Follow-up	−0.54 ± 0.81 (−2.61–0.71)	0.11 ± 1.04 (−1.73–2.25)	0.02
Change	−0.61 ± 0.82 (−3.30–0.31)	−0.08 ± 1.02 (−2.78–2.95)	0.06
Muscle area
Baseline	0.57 ± 0.82 (−0.72–2.30)	0.11 ± 0.80 (−1.04–1.58)	0.06
Follow-up	0.69 ± 0.87 (−0.78–2.63)	0.53 ± 0.90 (−0.71–2.81)	0.54
Change	0.08 ± 0.52 (−0.62–1.70)	0.36 ± 0.35 (−0.22–1.20)	0.06
Fat area
Baseline	0.77 ± 1.23 (−2.64–2.18)	0.57 ± 0.82 (−1.22–2.13)	0.53
Follow-up	0.37 ± 1.33 (−3.04–2.21)	0.55 ± 0.97 (−1.20–2.90)	0.62
Change	−0.32 ± 0.45 (−1.24–0.32)	−0.07 ± 0.33 (−1.09–0.55)	0.05

Early refers to participants with enrollment visit less than 6 months and late with enrollment visit more than 6 months after completion of ALL therapy. Data are presented as mean ± sd (range).