Table 1.
Direct | TA98 | TA100 | |||
Concentration (μg/well)b | Number of revertants per plate±SD | % inhibition of mutation | Number of revertants per plate±SD | % inhibition of mutation | |
15.625 | 294±16 | 29 | 216±19 | 27 | |
31.25 | 322±8 | 18 | 247±6 | 15 | |
62.5 | 302±12 | 26 | 196±14 | 34 | |
125 | 228±25 | 56 | 238±8 | 19 | |
250 | 196±19 | 69 | 172±11 | 43 | |
500 | 163±7 | 82 | 133±31 | 58 | |
SR | 119±21 | 19±5±8 | |||
Sodium azide (0.5) | ---- | 288+7 | |||
2-Nitrofluorene | 366±41 | --- | |||
Indirect | |||||
15.625 | 126±6 | 6 | 271±4 | 7 | |
31.25 | 121±9 | 12 | 279±16 | 3 | |
62.5 | 112±13 | 22 | 267±13 | 9 | |
125 | 86±24 | 49 | 224±11 | 31 | |
250 | 94±5 | 41 | 197±23 | 46 | |
500 | 79±7 | 57 | 164±8 | 63 | |
SR | 39±5 | 93±2 | |||
2-anthramine (0.1) | 132±17 | 284±6 |
Values are the mean±S.E.M.
a Without the S9 mix.
b n = 3.
c With the S9 mix, n = 3.