Table 2.

Effects of the subchronic oral administration of MEFL on hematological parameters in SD rats.

		Treatmenta
		Control	MEFL (mg/kg)
		0 mg/kg	750	1250	2500
Male rats
Hemoglobin	g/l	145.25±2.21	140.8±0.20	141.16±3.55	140.40±2.70
Total Red Blood Cells	1012/l	8.56±0.24	8.11±0.14	8.31±0.24	8.55±0.31
Total White Blood Cells	109/l	7.25±4.81	6.97±1.16	4.45±1.69	5.96±2.05
Neutrophils	%	33.25±6.99	35.50±2.42	38.25±6.99	37.20±6.01
Lymphocytes	%	58.50±6.10	56.67±2.78	58.50±6.13	57.20±5.11
Eosinophils	%	2.75±0.50	3.00±0.37	3.50±0.15	2.55±0.25
Monocytes	%	6.00±20.10	5.00±0.48	6.33±2.50	4.80±1.40
Basophils	%	0.00±0.00	0.00±0.00	0.00±0.00	0.00±0.00
Packed Cell Volume	%	45.00 ±0.81	44.65±0.99	41.00±0.86	43.80±0.99
Mean Corpuscular Volume	fl	54.50±0.57	55.17±0.65	56.83±0.40	57.80±0.80*)
Mean Corpuscular Hb	pg	17.66±0.50	18.37±0.19	18.33±0.5	18.60±0.80*)
Mean Corpuscular Hb Conc	g/l	328.75±6.65	326.9±0.5	325.66±7.99	321.00±4.47
Platelet Count	109/l	851.25±146.64	775.5±83.7	678.5±125.27*)	738.20±108.88
Female rats
Hemoglobin	g/l	149.66±4.35	141.20±0.83	143.50±5.42	140.50±3.32
Total Red Blood Cells	1012/l	8.18±0.7	7.81±0.20	8.14±0.40	8.04±0.50
Total White Blood Cells	109/l	15.40±2.02	15.49±0.75	15.51±3.80	15.53±1.02
Neutrophils	%	19.56±3.28	23.16±2.47	28.66±2.83	23.40±2.08
Lymphocytes	%	75.50±3.39	67.17±2.03	65.33±9.10	63.80±4.10*)
Eosinophils	%	3.80±0.07	3.00±0.51	5.80±0.50	3.80±0.07
Monocytes	%	6.16±0.31	6.3.00±1.53	6.80±0.48	6.70±0.45
Basophils	%	0.00±0.00	0.00±0.00	0.00±0.00	0.00±0.00
Packed Cell Volume	%	48.16±0.30	45.25±0.33	45.00±0.53*)	44.00±0.18*)
Mean Corpuscular Volume	fl	59.00±0.17	57.67±0.42	56.00±0.14*)	57.40±0.19
Mean Corpuscular Hb	pg	18.50±0.54	18.40±0.14	17.66±0.51*)	18.20±0.44
Mean Corpuscular Hb Conc	g/l	310.16±5.49	313.0±4.30	315.83±4.26	313.00±2.54
Platelet Count	109/l	980.16±25.49	860.3±24.4	977.50±20.26	772.60±21.50

Values are the mean ±S.E.M., ^a n = 6.

^*p<0.05.