Table 2. Correlation between the clinicopathological characteristics and expression of CTGF protein in NPC.
| Characteristics | n |
CTGF (%) |
P | |
|---|---|---|---|---|
| High expression | Low expression | |||
| Gender | ||||
| Male | 117 | 48(41.0) | 69 (59.0) | |
| Female | 56 | 30(53.6) | 26 (46.4) | 0.143 |
| Age (years) | ||||
| ≥50 | 79 | 32 (40.5) | 47 (59.5) | |
| <50 | 94 | 46 (48.9) | 48(51.1) | 0.286 |
| Smoking | ||||
| Yes | 31 | 9 (29.0) | 22 (71.0) | |
| No | 142 | 69 (48.6) | 73 (51.4) | 0.072 |
| Family tumor history | ||||
| Yes | 5 | 3(60.0) | 2(40.0) | |
| No | 168 | 75(44.6) | 93(55.4) | 0.659 |
| Recurrence | ||||
| Yes | 46 | 22(47.8) | 24(52.2) | |
| No | 127 | 56(44.1) | 71(55.9) | 0.730 |
| T classification | ||||
| T1–T2 | 122 | 62(50.8) | 60 (49.2) | |
| T3–T4 | 51 | 16 (31.4) | 35(68.6) | 0.020 |
| N classification | ||||
| N0–N1 | 95 | 51 (53.7) | 44(46.3) | |
| N2–N3 | 78 | 27(34.6) | 51 (65.4) | 0.014 |
| Distant metastasis | ||||
| Yes | 11 | 4(36.4) | 7(63.6) | |
| No | 162 | 74(45.7) | 88(54.3) | 0.756 |
| TNM Clinical stage | ||||
| I∼II | 58 | 35 (60.3) | 23 (39.7) | |
| III∼IV | 115 | 43(37.4) | 72(62.6) | 0.006 |