Table 3.
Worst acute nonhematologic and hematologic toxicity in patients receiving chemoradiation with conventional RT vs. IMRT
| Conventional RT |
IMRT |
P | |||
|---|---|---|---|---|---|
| n | % | n | % | ||
| Gastrointestinal | 0.061 | ||||
| Grade <3 | 28 | 75.7 | 29 | 39.5 | |
| Grade ≥3 | 11 | 29.7 | 5 | 9.6 | |
| Genitourinary | 0.090 | ||||
| Grade <3 | 35 | 94.6 | 14 | 26.9 | |
| Grade ≥3 | 2 | 5.4 | 0 | 0 | |
| Dermatologic | <0.0001 | ||||
| Grade <3 | 13 | 35.1 | 30 | 57.7 | |
| Grade ≥3 | 24 | 64.9 | 6 | 11.5 | |
| Leukopenia | 0.372 | ||||
| Grade <3 | 23 | 62.2 | 14 | 37.8 | |
| Grade ≥3 | 14 | 37.8 | 15 | 28.8 | |
| Anemia | 0.486 | ||||
| Grade <3 | 30 | 81.1 | 11 | 21.2 | |
| Grade ≥3 | 7 | 18.9 | 7 | 13.5 | |
| Thrombocytopenia | 0.559 | ||||
| Grade <3 | 31 | 83.9 | 11 | 21.2 | |
| Grade ≥3 | 3 | 8.1 | 11 | 21.2 | |
RT = radiation therapy; IMRT = intensity modulated radiation therapy.