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. 2013 Mar-Apr;6(2):47–55.

Figure 1.

Figure 1.

Overview of the EGFR pathway and downstream signaling pathways, including KRAS. Adapted with permission from Di Fiore F, et al: Molecular determinants of anti-EGFR sensitivity and resistance in metastatic colorectal cancer Br J Cancer 103:1765–1772, 2010.