Table 3.
Major Clinical Features of FRDA and Their Frequency from 3 Studies47
Symptom | Harding14 | Durr8 | Delatycki7 |
---|---|---|---|
Ataxia | 99 | 100 | 100 |
Dysarthria | 97 | 91 | 95 |
Absent lower limb reflexes | 99 | 87 | 74 |
Scoliosis | 79 | 60 | 78 |
Pes cavus | 55 | 55 | 74 |
Swallowing disturbance | - | 27 | - |
Sphincter disturbance | - | 23 | 41 |
Reduced vision | 18 | 13 | - |
Hearing impairment | 8 | 13 | - |
Cardiomyopathy on echocardiogram | - | 63 | 65 |
Diabetes/abnormal glucose tolerance | 10 | 32 | 8 |