Figure 5.

Opposing structural differences in the amygdala and medial prefrontal cortex are present in the young adults with the most extreme negative affect. A–C, Scatter plots represent the distribution of values for the left amygdala volumes and left medial prefrontal thickness estimates for the low (A), medium (B), and high (C) negative affect groups. Reported r values reflect Pearson correlations after partialing out variance associated with collection site, scanner software, estimated IQ, age, and sex. Estimated intracranial volume was additionally partialed from the amygdala volume estimate. D–F, Surface-based analyses reflect the correlation strength between left amygdala volume and thickness estimates at each vertex for the low (D), medium (E), and high (F) negative affect groups. Color bar reflects Pearson correlations.