TABLE I.
Genotype, diplotype and haplotype frequency for SNP1 and SNP2 in cases and controls
| Cases | Controls | |
|---|---|---|
| Genotypes for SNP1 | ||
| T,T | 0.665 | 0.731 |
| T,C | 0.306 | 0.244 |
| C,C | 0.029 | 0.023 |
| P-valuea | 7.5e−06 | |
| Genotypes for SNP2 | ||
| G,G | 0.665 | 0.676 |
| G,T | 0.306 | 0.301 |
| T,T | 0.030 | 0.023 |
| P-valuea | 0.25 | |
| Diplotypes for SNP1 and SNP2 | ||
| (T,T) (G,G) | 0.663 | 0.676 |
| (T,T) (G,T) | 0.002 | 0.057 |
| (TT) (T,T) | 0.000 | 0.000 |
| (T,C) (G,G) | 0.002 | 0.000 |
| (T,C) (G,T) | 0.305 | 0.244 |
| (T,C) (T,T) | 0.000 | 0.000 |
| (C,C) (G,G) | 0.000 | 0.000 |
| (C,C) (G,T) | 0.000 | 0.000 |
| (C,C) (T,T) | 0.029 | 0.023 |
| P-valuea | 1.15e−27 | |
| Haplotypes for SNP1 and SNP2 | ||
| TG | 0.817 | 0.827 |
| CT | 0.182 | 0.145 |
| TT | 0.001 | 0.028 |
| P-valuea | 8.36e−29 | |
a
P-value for significance of the frequency difference between cases and controls.