Table 1. Semiquantitative histopathological analysis.
The pathologist was blinded to the samples and graded for GVHD in multiple samples from animals treated with bone marrow transplant only (a non GVHD control), Vehicle, or either A2A agonist. The mean score (± SEM) is given for each tissue type.
| BM only | Vehicle | ATL370 | ATL1223 | |
|---|---|---|---|---|
| Liver | 1.250 ±0.957 | 3.125 ±0.354 | 0.500 ±0.548 | 1.400 ±0.894 |
| Skin | 1.200 ±0.837 | 3.000 ±0.577 | 1.429 ±0.535 | 1.750 ±0.463 |
| Colon | 0.600 ±0.548 | 2.286 ±0.756 | 0.600 ±0.894 | 1.600 ±0.548 |