Table 3.
Multivariable-adjusted* predictors of use of non-steroidal anti-inflammatory drugs after primary total knee arthroplasty
| Multivariable-adjusted* analysis, 2-year follow-up | Multivariable-adjusted* analysis, 5-year follow-up | |||||
|---|---|---|---|---|---|---|
| Odds ratio | (95% CI) | P-value | Odds ratio | (95% CI) | P-value | |
| Male gender (reference female) | 0.52 | (0.41, 0.64) | < 0.001a | 0.64 | (0.48, 0.85) | 0.002a |
| Age (reference ≤ 60 yrs) | ||||||
| > 60 to 70 yrs | 0.92 | (0.70, 1.20) | 0.53 | 0.57 | (0.41, 0.80) | 0.001a |
| > 70 to 80 yrs | 0.72 | (0.54, 0.95) | 0.02a | 0.56 | (0.39, 0.79) | 0.001a |
| > 80 yrs | 0.52 | (0.33, 0.82) | 0.005a | 1.00 | (0.61, 1.64) | 0.99 |
| Body mass index (reference < 25 kg/m2) | ||||||
| 25.0 to 29.9 | 1.20 | (0.85, 1.70) | 0.30 | 1.32 | (0.87, 2.00) | 0.20 |
| 30.0 to 34.9 | 1.08 | (0.76, 1.55) | 0.66 | 1.12 | (0.72, 1.74) | 0.63 |
| 35.0 to 39.9 | 1.44 | (0.98, 2.13) | 0.07 | 0.84 | (0.50, 1.41) | 0.50 |
| ≥ 40.0 | 1.64 | (1.08, 2.48) | 0.02a | 1.22 | (0.68, 2.20) | 0.50 |
| Deyo-Charlson index (5-point change) | 1.06 | (0.80, 1.41) | 0.68 | 0.93 | (0.67, 1.31) | 0.69 |
| Depression (reference no depression) | 1.39 | (1.04, 1.85) | 0.03a | 1.68 | (1.12, 2.51) | 0.01a |
| Anxiety (reference no anxiety) | 1.11 | (0.77, 1.61) | 0.56 | 0.85 | (0.49, 1.47) | 0.56 |
*Adjusted for American Society of Anesthesiologists (ASA) score, distance from the medical center, income, operative diagnosis and implant fixation in addition to all the variables in the table. aSignificant odds ratios and P-values; CI, confidence interval. Goodness of fit statistic calculated as quasi likelihood ratio with lower value indicating a better fit: 2 years, 3461.7; 5 years, 2098.4.