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. 2012 Nov 5;14(6):R241. doi: 10.1186/ar4084

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Copyright ©2012 Obata et al.; licensee BioMed Central Ltd.

This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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The number of chondrocyte-like cells after injections of phosphate-buffered saline (PBS) (control), platelet-poor plasma (PPP)-releasate, or platelet-rich plasma (PRP)-releasate. The numbers of chondrocyte-like cells in the inner anterior and posterior anulus fibrosus (AF) and the center of the nucleus pulposus (NP) were manually counted by using light microscopy. In the anterior AF, the number of chondrocyte-like cells in the PRP group was significantly higher than those of the PBS and PPP groups (P <0.01). The injection of PRP-releasate significantly increased the number of chondrocyte-like cells in the NP compared with that of the PBS group (P <0.01). Values are shown as mean ± standard error of the mean.