Table 2.
Inflammation and osteoblast-associated genes over-expressed in proteoglycan-induced spondylitis (PGISp) spines
| Gene | Fold change PGISp/Control | P-value | Gene symbol |
|---|---|---|---|
| Matrix metallopeptidase 3 | 5.29 | 3.50E-05 | Mmp3 |
| Matrix metallopeptidase 13 | 2.26 | 0.0086 | Mmp13 |
| Tissue inhibitor of metalloproteinase 1 | 3.48 | 0.0003 | Timp1 |
| Interleukin 1, beta | 1.57 | 0.0087 | Il1b |
| Interleukin 1 receptor, type II | 1.28 | 0.0000 | Il1r2 |
| interleukin 28 receptor alpha | 1.18 | 0.0068 | Il28ra |
| Signal transducer and activator of transcription 1 | 1.18 | 0.0150 | Stat1 |
| Signal transducer and activator of transcription 3 | 1.21 | 0.0039 | Stat3 |
| Bone sialoprotein | 2.62 | 0.0001 | Ibsp |
| Collagen Type I | 2.51 | 0.0005 | Col1a1 |
| Collagen Type III | 2.42 | 0.0004 | Col3a1 |
| Osteocalcin | 1.50 | 0.0297 | Bglap1 |