Table 2.
Correlations of serum levels for BLyS and APRIL to lupus activity parameters, pathological scores, and renal and systemic involvement at baseline.
| BLyS | APRIL | ||
|---|---|---|---|
| Renal parameters | |||
| R_SLEDAI | -0.17 | 0.22 | |
| Serum creatinine | mg/dl | 0.06 | 0.06 |
| Erythrocyturia | cells/high power field | -0.13 | 0.06 |
| Urine protein | g/day | -0.05 | 0.44** |
| Activity score | -0.11 | 0.34* | |
| Chronicity score | 0.25 | 0.20 | |
| Lupus parameters | |||
| ANA titer | -0.20 | 0.02 | |
| Anti-dsDNA titer | -0.28 | 0.23 | |
| Complement factor 3 | mg/dl | 0.46** | -0.44** |
| Total leukocyte count | cells/mm3 | -0.49*** | 0.26 |
| Polymorph | cells/mm3 | -0.40** | 0.18 |
| Lymphocyte | cells/mm3 | -0.42*** | -0.14 |
| Treatment | |||
| Prednisolone | mg/day | 0.46*** | 0.25 |
| Mycophenolate | mg/day | 0.37** | -0.09 |
ANA, antinuclear antibody; APRIL, a proliferation-inducing ligand; BlyS, B lymphocyte activation protein; R_SLEDAI, renal Systemic Lupus Erythematous Disease Activity Index. *P < 0.05, **P < 0.01, ***P < 0.001.