Table 2.
Lower Extremity Function (mSPPB) Trajectory Estimates for the Full Sample†
Unadjusted‡ | Survival adjusted‡ | Health Adjusted‡ | MRFs Adjusted‡ | Fully Adjusted Except Survival | Fully Adjusted‡ | |
---|---|---|---|---|---|---|
(M0) | (M1) | (M2.1) | (M2.2) | (M3.1) | (M3.2) | |
Fixed effects | ||||||
Intercept§ | ||||||
Intercept|| | 5.27* | 4.86* | 4.75* | 4.33* | 5.20* | 4.75* |
Women | −0.73** | −1.08* | −0.76* | −0.40 | −0.18 | −0.41 |
Survival | — | 0.73* | 0.44* | 0.53* | — | 0.39* |
Linear slope | ||||||
Intercept | −0.67* | −0.92* | −0.74* | −0.82* | −0.51* | −0.66* |
Women | 0.21* | 0.18* | 0.17* | 0.16** | 0.16** | 0.15** |
Survival | — | 0.13* | 0.07* | 0.10* | — | 0.06* |
Quadratic slope | ||||||
Intercept | −0.01** | −0.04*** | −0.02 | −0.04*** | −0.03*** | −0.02 |
Women | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 |
Survival | — | 0.00 | −0.01 | 0.00 | — | −0.01 |
Cubic slope | ||||||
Intercept | 0.01* | 0.00* | 0.01* | 0.01** | 0.01** | 0.01** |
Women | −0.00 | −0.00 | −0.00 | −0.00 | −0.00 | −0.00 |
Survival | — | −0.00 | −0.00*** | −0.00 | — | −0.00*** |
Random effects (variance) | ||||||
Intercept | 8.67* | 5.93* | 4.36* | 4.05* | 4.24* | 3.76* |
Linear slope | 0.11* | 0.09* | 0.07* | 0.08* | 0.07* | 0.06* |
Quadratic slope | 0.00* | 0.00* | 0.00* | 0.00* | 0.00* | 0.00* |
Cubic slope | 0.00*** | 0.00*** | 0.00*** | 0.00 | 0.00*** | 0.00*** |
Level-1, E¶ | 1.94 | 1.91 | 1.83 | 1.88 | 1.83 | 1.81 |
Deviance | 17354.4 | 17104.1 | 16937.1 | 17001.1 | 16991.6 | 16938.4 |
Estimated parameters (nr.) | 11 | 11 | 11 | 11 | 11 | 11 |
Notes: mSPPB = modified Short Physical Performance Battery score.
† N = 690 participants/4111 observations.
‡Unadjusted M0 is the time-only model; M1,adjusted for length-of-survival; M2.1, adjusted for length-of-survival and health status; M2.2, adjusted for length-of-survival and modifiable risk factors, but not for health status; M3.1, adjusted for health status and MRFs, but not for length-of-survival; M3.2, fully adjusted for length-of-survival, health status and MRFs. M1, M2.1, M2.2, M3.1, and M3.2 tested with and without adjustment for age-at-baseline, education, race, and living arrangement; results from adjusted models are presented in the table.
§Time(t) centered at its grand mean in all models; consequently, mSPPB intercept should be interpreted as mSPPB score at mean follow-up time (6 years).
||Intercept for each fixed effect represents the estimate when all other variables are held constant as appropriate at 0 (binary variables) or at sample mean (continuous variables).
¶Level 1, E represents the residual intra-individual (ie, wave-to-wave) variation in mSPPB.
*p value < .001, **p value < .01, ***p value < .05.