Table 4.
Multivariate Associations of a Phenotype in Question Measured in Children (outcome) With Physiological Indices Measured in Their Parents (predictors)
Model | Phenotypes | Model A | Model B | |||||
---|---|---|---|---|---|---|---|---|
Outcome | Predictors | β | SE | p Value | β | SE | p Value | |
Model 1 | BMIC | BGP | −0.72 | 2.00 | 7.2E-1 | −2.32 | 2.06 | 2.6E-1 |
HDL-CP | −4.05 | 1.33 | 2.6E-3 | −3.06 | 1.36 | 2.5E-2 | ||
TGP | 0.75 | 0.77 | 3.4E-1 | −0.16 | 0.79 | 8.4E-1 | ||
SBPP | 5.37 | 1.84 | 7.0E-3 | 3.66 | 1.89 | 6.5E-2 | ||
BMIP | N/I | N/I | N/I | 0.24 | 0.04 | 8.8E-5 | ||
Model 2 | HtnC | BMIP | 7.7E-3 | 3.0E-3 | 1.1E-2 | 7.1E-3 | 3.0E-3 | 1.9E-2 |
BGP | 2.2E-2 | 1.8E-1 | 9.0E-1 | −8.5E-4 | 1.8E-1 | 1.0E+0 | ||
HDL-CP | 3.9E-2 | 1.2E-1 | 7.4E-1 | 3.1E-2 | 1.1E-1 | 7.9E-1 | ||
TGP | 7.6E-2 | 6.8E-2 | 2.7E-1 | 5.9E-2 | 6.7E-2 | 3.9E-1 | ||
HtnP | N/I | N/I | N/I | 8.1E-2 | 2.6E-2 | 7.6E-3 | ||
Model 3 | T2DC | BMIP | 2.1E-3 | 1.4E-3 | 1.3E-1 | 1.8E-3 | 1.4E-3 | 1.8E-1 |
LDL-CP | −2.5E-3 | 1.8E-3 | 1.6E-1 | −1.6E-3 | 1.8E-3 | 3.6E-1 | ||
TGP | 3.6E-2 | 3.2E-2 | 2.6E-1 | 3.5E-2 | 3.1E-2 | 2.7E-1 | ||
SBPP | 4.9E-2 | 9.6E-2 | 6.1E-1 | 4.0E-2 | 9.6E-2 | 6.8E-1 | ||
DBPP | −2.2E-3 | 6.3E-3 | 7.4E-1 | −3.0E-3 | 6.3E-3 | 6.5E-1 | ||
T2DP | N/I | N/I | N/I | 5.8E-2 | 2.8E-2 | 1.3E-1 |
Notes: Subscript “P” means parents and subscript “C” means their children.
N/I = not included in the model; other notations and the models adjustments are in Table 2.
The sample size for all models is about N = 1,539 with the exception of N = 1,459 for Model 1B.