Table 2.
Hydrogen bonding contacts of TMH1 and TMH2
| A. TMH1 | |
| Ser188 – | Asp58 |
| Asp380 (water-mediated) | |
| Lys189 – | Asp58 (water-mediated) |
| Gln191 – | Met185 |
| Ser194 – | Th87 |
| Asn377 | |
| Leu 196 – | Tyr278 (water-mediated) |
| Asn 197 – | Asp91 |
| Ser93 (water-mediated) | |
| Asn 205 – | Lys332 (water-mediated) |
| Ser 206 – | Lys332 |
| Leu 207 – | Gly208 |
| Lys280 | |
| Asp 210 – | Lys219 |
| Glu282 (water-mediated) | |
| Asn 216 – | Lys69 |
| B. TMH2 | |
| Ser285 – | Glu388 (water-mediated) |
| Ser286 – | Ser386 |
| Glu388 | |
| Ser287 – | Lys220 |
| Lys288 – | Glu388 (water-mediated) |
| Gln291 – | Glu183 (water-mediated) |
| Lys295 – | Glu183 |
| Leu297 – | Arg342 |
| Ile298 – | Arg342 (water-mediated) |