Figure 2. Genome-wide association study of female abdominal pigmentation.

A) Manhattan plot for abdominal pigmentation in the full data set (including all five replicates). The–log₁₀ p-values are plotted against the position on each chromosome. The horizontal dashed line indicates the genome-wide significance threshold at an FDR of 0.05. The red bars indicate candidate genes previously shown to affect pigmentation. B) Detailed view of the tan (left), bab1 (middle) and ebony (right) regions. The positions on the x-axis are indicated in kb. The red bars indicate regulatory regions previously shown to affect pigmentation. C) Detailed view of top ranked polymorphisms located within or close to the three pigmentation genes. For every gene, the most significant SNPs fall in regulatory regions.