Skip to main content
. 2013 Jun 6;9(6):e1003558. doi: 10.1371/journal.pgen.1003558

Figure 5. H3.3 nucleosome splitting events are better markers for active transcription than H3.3 nucleosome occupancy.

Figure 5

(A) Split H3.3 nucleosomes were enriched in the top 25% expression level genes, as compared to the total H3.3 nucleosomes or non-split H3.3 nucleosomes. Non-split H3.3 nucleosomes were enriched in the bottom 25% expression level genes. P values were calculated with chi-square test. ***P<0.001, **P<0.01, #P>0.1. (B) After normalization against the H3.3 occupancy, the split but not the non-split H3.3 nucleosomes were enriched at active genes. H3.3 nucleosomes at the entire genes were analyzed together.