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. 2013 Jun 6;8(6):e65548. doi: 10.1371/journal.pone.0065548

Figure 9. Conclusion – Major fraction of GP5 from PRRSV type 2 does not contain the “decoy epitope”.

Figure 9

Schematic representation of GP5 fractions as evidenced in this study. The signal peptide of GP5 is predominantly cleaved at site 2 (A26|V27; black arrow), but is also cleaved in minor quantities at site 1 (A26|V27, thin grey arrow). The “decoy epitope” (magenta) is preserved only in GP5 cleaved at site 1. The neutralizing epitope (green) is present in either case. Heterogeneity occurs also at non-conserved glycosylation sites (red). The fraction of GP5 with the “decoy epitope” contains carbohydrates at either both N30 and N33, or only at N33 or none of these sites. A subfraction of site 2-cleaved GP5 does not contain a carbohydrate at N33. Conserved glycosylation sites are in brown.