Table 2. Biological data (Median (IQR)).
High HDL | Low HDL | p | |
N = 250 | N = 362 | ||
CRP, mg/L | 4.0(3.0–10.7) | 6.5(3.0–18.0) | <0.001 |
Homocysteine, µmol/L | 13(10–17 | 12(10–17 | 0.239 |
Creatinine clearance, ml/min | 75(54–92) | 80(52–107) | 0.311 |
Glucose, mmol/L | 6.84(5.72–8.37) | 6.93(5.77–9.32) | 0.211 |
HbA1c, % | 5.8(5.5–6.3) | 5.9(5.6–6.7) | 0.082 |
HDL-cholest, mg/dL | 54(47–64) | 33(27–38) | <0.001 |
LDL-cholest, mg/dL | 121(94–152) | 125(94–153) | 0.390 |
Total-cholest, mg/dL | 199(168–227) | 191(158–224) | 0.023 |
Triglycerides, mg/dL | 93(68–135) | 138(95–199) | <0.001 |
ADMA, µmol/L | 0.50(0.41–0.73) | 0.69(0.47–1.02) | <0.001 |
SDMA, µmol/L | 0.52(0.42–0.70) | 0.51(0.38–0.71) | 0.120 |
L-arginine, µmol/L | 83.9(68.7–114.4) | 91.1(72.5–120.9) | 0.064 |
L-arg/ADMA ratio | 163(118–225) | 132(92–199) | <0.001 |
Low HDL was defined as HDL <40 mg/dL in men and <50 mg/dL in women.
ADMA: Asymmetric dimethylarginine; CRP: C-reactive protein; HbA1c: glycated hemoglobin; HDL-C: high-density lipoprotein; LDL-C: low-density lipoprotein; SDMA: Symmetric dimethylarginine.