Table 6. Pearson’s r or Spearman’s ρ correlation coefficients between tear protein and clinical parameter (significance p<0.05).
| Test variable | OSDI | TFBUT | Schirmer test 1 | Cornea NEI | Conjunctiva NEI | DE severity score |
|---|---|---|---|---|---|---|
|
LYS-C |
r=- 0.28
p=0.0001 |
r=0.11
p=0.12 |
r=0.12
p=0.12 |
r=-0.28
p=0.0001 |
r=-0.16
p=0.01 |
ρ=- 0.39
p<0.0001 |
|
LACTO |
r=-0.35
p<0.0001 |
r=0.35
p<0.0001 |
r=0.07
p=0.2 |
r=-0.30
p<0.0001 |
r=-0.24
p=0.0006 |
ρ=- 0.36
p<0.0001 |
|
LIPOC-1 |
r=- 0.31
p<0.0001 |
r=0.39
p<0.0001 |
r=0.16
p=0.02 |
r=- 0.42
p<0.0001 |
r=-0.23
p=0.001 |
ρ=- 0.57
p<0.0001 |
|
TRANSF |
r=-0.28
p<0.0001 |
r=0.17
p=0.01 |
r=-0.20
p=0.003 |
r=-0.30
p<0.0001 |
r=-0.24
p=0.0006 |
ρ=-0.37
p<0.0001 |
|
ALB |
r=0.09
p=0.1 |
r=- 0.22
p=0.001 |
r=-0.15
p=0.4 |
r=0.16
p=0.02 |
r=0.21
p=0.002 |
ρ=0.52
p<0.0001 |
|
ZAG-2 |
r=-0.16
p=0.03 |
r=0.41
p<0.0001 |
r=0.13
p=0.7 |
r=-0.3
p=0.001 |
r=-0.12
p=0.2 |
ρ=-0.35
p<0.0001 |
| TP | r=-0.35 p<0.0001 | r=0.33 p<0.0001 | r=-0.06 p=0.4 | r=- 0.36 p<0.0001 | r=-0.33 p=0.001 | ρ=- 0.54 p<0.0001 |
OSDI, ocular surface disease index; TFBUT, tear film break-up time, Corneal and Conjunctival vital staining scored by the National Eye Institute (NEI) grade system. DE severity was scored as 1 or 2 according to Asbell and Lemp [14].