Table 2. The genotype distribution of VEGF-A polymorphisms used in this study.
| Polymorphism | Reference | Ethnicity | Type of cases | Cases | Controls | HWE |
|---|---|---|---|---|---|---|
|
rs1413711 |
CC/CT/TT |
CC/CT/TT |
||||
| [23] |
Asian |
wet AMD |
81/58/20 |
81/50/9 |
0.73 |
|
| [24] |
Mixed |
total AMD |
65/66/29 |
67/65/8 |
0.12 |
|
| dry AMD |
14/14/8 |
|||||
| wet AMD |
51/52/21 |
|||||
| [16] |
Asian |
total AMD |
57/80/53 |
50/85/42 |
0.61 |
|
| dry AMD |
29/46/29 |
|||||
| wet AMD |
28/34/24 |
|||||
| [13] |
Caucasian |
wet AMD |
17/18/10 |
19/54/21 |
0.14 |
|
|
rs833061 |
TT/TC/CC |
TT/TC/CC |
||||
| [23] |
Asian |
wet AMD |
81/58/20 |
81/50/9 |
0.73 |
|
| [15] |
Caucasian |
total AMD |
48/191/26 |
60/63/11 |
0.32 |
|
| dry AMD |
13/67/8 |
|||||
| wet AMD |
35/124/18 |
|||||
| [16] |
Asian |
total AMD |
116/66/8 |
116/60/4 |
0.23 |
|
| dry AMD |
60/38/6 |
|||||
| wet AMD |
56/28/2 |
|||||
| [28] |
Caucasian |
total AMD |
154/259/153 |
40/78/39 |
0.93 |
|
| dry AMD |
27/43/30 |
|||||
| wet AMD |
92/158/86 |
|||||
|
rs2010963 |
GG/GC/CC |
GG/GC/CC |
||||
| [23] |
Asian |
wet AMD |
54/70/35 |
39/74/27 |
0.44 |
|
| [15] |
Caucasian |
total AMD |
164/84/17 |
85/44/5 |
0.81 |
|
| dry AMD |
47/30/11 |
|||||
| wet AMD |
117/54/6 |
|||||
| [16] |
Asian |
total AMD |
40/132/18 |
34/116/30 |
0 |
|
| dry AMD |
24/70/10 |
|||||
| wet AMD |
16/62/8 |
|||||
|
rs3025039 |
CC/CT/TT |
CC/CT/TT |
||||
| [23] |
Asian |
wet AMD |
114/33/12 |
92/40/8 |
0.2 |
|
| [26] |
Caucasian |
total AMD |
175/48/3 |
190/54/4 |
0.94 |
|
| [16] |
Asian |
total AMD |
120/58/12 |
134/42/4 |
0.74 |
|
| dry AMD |
75/27/2 |
|||||
| wet AMD | 45/31/10 |