Table 2. Linearity of progression and time until first consistent significant difference from baseline for the entire cohort of animals (N = 45).

Measure	Normalized mean absolute residual from fitted line†	Time of disease onset (weeks)
Resistance *	-	-
Reactance	0.06	8
Phase	0.06	8
Paw grip endurance	0.17	9
CMAP amplitude	0.10	12
MUNE	0.15	15
Weight *	-	-
Motor score	0.20	16

^*Resistance and weight values did not change significantly from baseline;

^†Residuals from fitted line normalized to mean value of that parameter across all weeks of measurement.