Table 2. Receiver Operator Characteristic (ROC) comparison of sensitivity and specificity of ELISA tests for Whole Mite Antigen extract (WMA) and Sar s 14.3 from week 8 to 20 post-infestation.
WMA | Sar s 14.3 | |||||
IgG | IgG1 | IgG2 | IgG | IgG1 | IgG2 | |
AUC a | 0.95 | 0.99 | 0.98 | 0.91 | 0.97 | 0.91 |
S.E b | 0.019 | 0.004 | 0.012 | 0.025 | 0.015 | 0.027 |
Cut-off | 0.43 | 0.49 | 0.45 | 0.93 | 1.02 | 0.95 |
Sensitivity c | 90% | 100% | 95% | 90% | 97% | 87% |
Specificity c | 90% | 90% | 90% | 70% | 92% | 91% |
AUC- area under curve.
S.E- standard error.
Optimum sensitivity and specificity determined at cut-off indicated.