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. 2013 Jun 6;8(6):e65354. doi: 10.1371/journal.pone.0065354

Table 2. Receiver Operator Characteristic (ROC) comparison of sensitivity and specificity of ELISA tests for Whole Mite Antigen extract (WMA) and Sar s 14.3 from week 8 to 20 post-infestation.

WMA Sar s 14.3
IgG IgG1 IgG2 IgG IgG1 IgG2
AUC a 0.95 0.99 0.98 0.91 0.97 0.91
S.E b 0.019 0.004 0.012 0.025 0.015 0.027
Cut-off 0.43 0.49 0.45 0.93 1.02 0.95
Sensitivity c 90% 100% 95% 90% 97% 87%
Specificity c 90% 90% 90% 70% 92% 91%
a

AUC- area under curve.

b

S.E- standard error.

c

Optimum sensitivity and specificity determined at cut-off indicated.