Table 2. Association of PhIP-DNA Adduct Levels with Prostate Cancer.
Sample PhIP-DNA Adduct Level |
ORa | 95% CI | P value |
---|---|---|---|
Whole Sample (n=534 case-control pairs) | |||
2nd Quartile | 1.20 | 0.83-1.72 | 0.34 |
3rd Quartile | 1.29 | 0.87-1.92 | 0.20 |
4th Quartile | 1.25 | 0.76-2.07 | 0.38 |
Trend Test | 0.36 | ||
High PhIP levela | 1.16 | 0.84-1.59 | 0.37 |
African Americans (n=213 case-control pairs) | |||
2nd Quartile | 1.32 | 0.75-2.32 | 0.33 |
3rd Quartile | 0.96 | 0.49-1.86 | 0.90 |
4th Quartile | 0.73 | 0.32-1.63 | 0.44 |
Trend Test | 0.35 | ||
High PhIP levela | 0.76 | 0.44-1.32 | 0.33 |
Whites (n= 321 case-control pairs) | |||
2nd Quartile | 1.12 | 0.69-1.81 | 0.65 |
3rd Quartile | 1.48 | 0.90-2.44 | 0.13 |
4th Quartile | 1.73 | 0.89-2.34 | 0.10 |
Trend Test | 0.07 | ||
High PhIP levela | 1.44 | 0.97-2.14 | 0.07 |
all risk estimates use lowest level as referent group
above median level in controls