Table 1. Systolic blood pressure and cardiac beat-to-beat interval over 8 weeks after left renal artery clipping in Wistar rats.
Initial | Week 1 | Week 2 | Week 3 | Week 4 | Week 5 | Week 6 | Week 7 | Week 8 | |
Systolic blood pressure, mm Hg | |||||||||
Sham (n = 16) | 126.5±7.1 | 127.6±10.2 | 127.2±10.3 | 128.8±10.6 | 127.4±10.5 | 128.2±10.6 | 125.5±8.0 | 124.5±10.7 | 130.3±7.2 |
Stable hypertension (n = 25) | 121.7±9.2 | 130.0±14.1 | 150.8±22.4* | 174.4±21.5* | 180.0±21.6* | 178.4±24.9* | 188.6±29.3* | 181.4±26.2* | 176.1±22.4* |
Non-stable hypertension(n = 9) | 127.3±6.1 | 136.2±13.2 | 145.8±19.7* | 144.6±23.0 | 135.2±9.3 | 135.0±11.3 | 146.1±9.4* | 143.2±10.5 | 129.3±6.2 |
Without hypertension (n = 34) | 126.1±8.1 | 126.3±10.6 | 131.8±11.0 | 127.5±13.6 | 127.4±12.4 | 129.3±10.2 | 123.5±11.7 | 123,8±9,0 | 124.3±11.7 |
Beat-to-beat interval, ms | |||||||||
Sham (n = 16) | 159.4±15.2 | 158.7±16.1 | 159.8±14.4 | 159.5±10.3 | 163.0±12.8 | 159.4±11.9 | 173.2±13.4 | 177.6±10.7 | 178.5±13.2 |
Stable hypertension (n = 25) | 164.6±18.1 | 164.5±15.6 | 160.8±12.3 | 155.5±12.5 | 165.4±15.5 | 164.7±17.6 | 166.4±14.0 | 166.6±16.3 | 168.2±16.3 |
Non-stable hypertension(n = 9) | 172.7±15.2 | 173.2±23.5 | 168.1±19.2 | 163.4±21.4 | 182.5±15.2 | 181.7±23.7 | 177.8±25.4 | 176.3±17.3 | 184.2±13.4 |
Without hypertension (n = 34) | 157.6±16.3 | 159.4±14.3 | 160.4±12.8 | 163.4±12.4 | 167.7±12.5 | 167.9±12.7 | 169.4±13.3 | 166.6±13.2 | 170.9±14.6 |
p<0.05 versus controls.