Table 1. Compilation of absolute numbers of CMP and GMP of bone marrow cells in steady state and at day 7 after infection with Plasmodium chabaudi in C57BL/6 mice and various mutant mouse strains.
BM cell number per femur/pair (×103) | |||
CMP | GMP | ||
C57BL/6 | uninfected | 36.1±5.8 | 20.4±7.3 |
Day 7 post infection | 8.4±2.9 | 8.1±3.9 | |
Ratio uninfected∶infected | 4.3 | 2.5 | |
% at day 7 post infection | 23% | 39% | |
Ifngr1−/− | uninfected | 37.2±11.8 | 38.0±15.5 |
Day 7 post infection | 30.7±11.0 | 51.3±12.8 | |
Ratio uninfected∶infected | 1.2 | 0.74 | |
% at day 7 post infection | 83% | 135% | |
Ccr2−/− | uninfected | 60.6±5.0 | 41.8±8.4 |
Day 7 post infection | 50.7±7.2 | 59.3±6.5 | |
Ratio uninfected∶infected | 1.2 | 0.7 | |
% at day 7 post infection | 83% | 142% | |
Myd88−/− Trif−/− | uninfected | 60.9±5.6 | 40.9±1.9 |
Day 7 post infection | 32.9±6.5 | 26.4±5.8 | |
Ratio uninfected∶infected | 1.9 | 1.5 | |
% at day 7 post infection | 54% | 65% |
CMP: LIN− c-Kit+ CD27+ CD34+ CD16/32−.
GMP: LIN− c-Kit+ CD27+ CD34+ CD16/32+.